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Article

Polymorphisms in the VEGFA promoter are associated with susceptibility to hepatocellular carcinoma by altering promoter activity.

International journal of cancer - 1 Sept 2013

Wu Xiaopan, Xin Zhenhui, Zhang Wei, Wu Jia, Chen Kangmei, Wang Huifen, Zhu Xilin, Pan Liping, Li Zhuo, Li Hui, Liu Ying

Abstract excerpt

Accumulated evidences indicate that single nucleotide polymorphisms (SNP) in angiogenesis and tumorigenesis related genes are associated with risk of hepatocellular carcinoma (HCC). Vascular endothelial growth factor A (VEGFA), one of the most significant mediators of angiogenesis, plays an important role in carcinogenesis and development via promoting tumor growth. We carried out a two-stage association study in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

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Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 23404364
DOI: 10.1002/ijc.28109

Genes

VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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