Article
Vascular endothelial growth factor haplotypes associated with childhood obesity.
DNA and cell biology - 1 Sept 2011
Belo Vanessa A, Souza-Costa Debora C, Luizon Marcelo R, Izidoro-Toledo Tatiane C, Lanna Carla M, Pinheiro Lucas C, Tanus-Santos Jose E
Abstract excerpt
Expansion of adipose tissue in obesity is associated with angiogenesis and adipose tissue mass depends on neovascularization. Vascular endothelial growth factor (VEGF) is the main angiogenic factor in the adipose tissue, and VEGF expression is tightly regulated at both transcriptional and translational levels. However, no previous study has tested the hypothesis that genetic polymorphisms in the VEGF gene could...
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