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Article

Effect of genetic polymorphisms of vascular endothelial growth factor on left ventricular hypertrophy in patients with systemic hypertension.

The American journal of cardiology - 1 Feb 2014

Lacchini Riccardo, Luizon Marcelo Rizzatti, Gasparini Sandra, Ferreira-Sae Maria C, Schreiber Roberto, Nadruz Wilson, Tanus-Santos Jose E

Abstract excerpt

Vascular endothelial growth factor (VEGF) is a cytokine involved in angiogenesis and upregulated during adaptive heart hypertrophy. Downregulation of VEGF seems to trigger the transition from adaptive to dilated cardiac hypertrophy. We investigated for the first time whether 3 clinically relevant polymorphisms in the VEGFA gene are associated with altered echocardiographic parameters in hypertensive patients. We...

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Share to Disease Progression
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Predisposition to Disease

Share to Hypertension

Share to Hypertrophy, Left Ventricular

Share to Polymorphism, Genetic

Share to Vascular Endothelial Growth Factor A

Source

Identifiers

PMID: 24321896
DOI: 10.1016/j.amjcard.2013.10.034

Genes

VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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