Article
Sources of variability in genetic association studies: insights from the analysis of hepatic lipase (LIPC).
Human mutation - 1 May 2002
Shohet Ralph V, Vega Gloria L, Bersot Thomas P, Mahley Robert W, Grundy Scott M, Guerra Rudy, Cohen Jonathan C
Abstract excerpt
Genetic association studies have been widely used to identify loci that influence plasma lipoprotein concentrations, but few of the associations reported have proved consistently reproducible across different study populations. This lack of consistency is a widely recognized limitation of associa...
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