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Article

Multiscale cardiac modelling reveals the origins of notched T waves in long QT syndrome type 2.

Nature communications - 25 Sept 2014

Sadrieh Arash, Domanski Luke, Pitt-Francis Joe, Mann Stefan A, Hodkinson Emily C, Ng Chai-Ann, Perry Matthew D, Taylor John A, Gavaghan David, Subbiah Rajesh N, Vandenberg Jamie I, Hill Adam P

Abstract excerpt

The heart rhythm disorder long QT syndrome (LQTS) can result in sudden death in the young or remain asymptomatic into adulthood. The features of the surface electrocardiogram (ECG), a measure of the electrical activity of the heart, can be equally variable in LQTS patients, posing well-described diagnostic dilemmas. Here we report a correlation between QT interval prolongation and T-wave notching in LQTS2...

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PMID: 25254353
DOI: 10.1038/ncomms6069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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