Article
Nuclear localization of protein kinase U-alpha is regulated by 14-3-3.
The Journal of biological chemistry - 27 Aug 1999
Zhang S, Xing H, Muslin A J
Abstract excerpt
14-3-3 proteins are intracellular, dimeric molecules that bind to and modify the activity of several signaling proteins. We used human 14-3-3zeta as a bait in the yeast two-hybrid system to screen a murine embryonic cDNA library. One interacting clone was found to encode the carboxyl terminus of a putative protein kinase. The coding sequence of the human form (protein kinase Ualpha, PKUalpha) of this protein...
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