Article
Comprehensive evaluation of the neuropeptide-Y gene variants in the risk of obesity: a case-control study and meta-analysis.
Pharmacogenetics and genomics - 1 Oct 2015
Zain Shamsul Mohd, Mohamed Zahurin, Jalaludin Muhammad Yazid, Fauzi Fatin, Hamidi Anahita, Zaharan Nur Lisa
Abstract excerpt
BACKGROUND: Orexigenic actions mediated by neuropeptide-Y (NPY) promote body weight regulation. Genetic variations in the NPY gene could therefore influence susceptibility to obesity, but results have been conflicting. We have carried out, for the first time, a case-control study to examine the effect of NPY rs16147 and rs5574 variants with the risk of obesity in Asians and also a meta-analysis to summarize the...
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