Article
Detection of hepatitis B virus genotypes using oligonucleotide chip among hepatitis B virus carriers in Eastern China.
World journal of gastroenterology - 7 Apr 2007
Tang Xiang-Rong, Zhang Ji-Shen, Zhao Hui, Gong Yu-Hua, Wang Yong-Zhong, Zhao Jian-Long
Abstract excerpt
AIM: To determine the genotype distribution of hepatitis B virus (HBV) with a newly oligonucleotide chip assay among the HBV carriers in Eastern China. METHODS: An assay using oligonucleotide chip was developed for detection of HBV genotypes in serum samples from HBV DNA-positive patients in Eastern China. This method is based on the principle of reverse hybridization with Cy5-labeled amplicons hybridizing to...
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