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Article

Stability and homogeneity of transgene expression in isogenic cells.

Journal of molecular medicine (Berlin, Germany) - 1 Jan 2006

Liu Weimin, Xiong Yuanzhu, Gossen Manfred

Abstract excerpt

Genetically engineered cells are an important tool not only for basic research applications, but also for biotechnology and molecular medicine. Among the issues yet to be solved for this technology are the consequences of randomly integrating DNA into a cell's genome. The problems encountered range from unpredictable expression levels to safety concerns. Recombinase-mediated chromosome engineering is a popular...

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Identifiers

PMID: 16328206
DOI: 10.1007/s00109-005-0711-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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