Article
Bone morphogenetic proteins.
Growth factors (Chur, Switzerland) - 1 Dec 2004
Chen Di, Zhao Ming, Mundy Gregory R
Abstract excerpt
Bone morphogenetic proteins (BMPs) are multi-functional growth factors that belong to the transforming growth factor beta (TGFbeta) superfamily. The roles of BMPs in embryonic development and cellular functions in postnatal and adult animals have been extensively studied in recent years. Signal transduction studies have revealed that Smad1, 5 and 8 are the immediate downstream molecules of BMP receptors and play...
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