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Article

Distinct roles of bone morphogenetic proteins in osteogenic differentiation of mesenchymal stem cells

8 Feb 2007

Abstract excerpt

Efficacious bone regeneration could revolutionize the clinical management of many bone and musculoskeletal disorders. Bone morphogenetic proteins (BMPs) can regulate the differentiation of mesenchymal stem cells into cartilage, bone, tendon/ligament, and fat lineages. Early data documented the osteogenic potential of rhBMP2 and rhBMP7/OP-1. However, prior to this work that summarized several of our recent...

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PMID: 17290432
DOI: 10.1002/jor.20359

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