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Article

Impaired fear memory and decreased hippocampal neurogenesis following olfactory bulbectomy in rats.

The European journal of neuroscience - 1 Dec 2005

Jaako-Movits Külli, Zharkovsky Alexander

Abstract excerpt

It has been proposed that a decrease in adult hippocampal neurogenesis provides a biological and cellular basis for major depression. The olfactory bulbectomy (OB) in rats is widely accepted as an animal model of depression. In the present study, we investigated the effect of OB on memory formation in the memory tasks related to the hippocampal function and adult hippocampal neurogenesis. OB induced a behavioural...

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Identifiers

PMID: 16324122
DOI: 10.1111/j.1460-9568.2005.04481.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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