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Article

Creutzfeldt-Jakob disease risk and PRNP codon 129 polymorphism: necessity to revalue current data.

European journal of neurology - 1 Dec 2005

Mitrová E, Mayer V, Jovankovicová V, Slivarichová D, Wsólová L

Abstract excerpt

The polymorphism at codon 129 (M129V) of the prion protein gene (PRNP) is a recognized genetic marker for susceptibility to Creutzfeldt-Jakob disease (CJD) in the Caucasians. The distribution of this polymorphism in healthy individuals provides an important starting point for the evaluation of CJD risk in the general population. Early studies of reference population cohorts demonstrated that methionine/valine...

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Identifiers

PMID: 16324095
DOI: 10.1111/j.1468-1331.2005.01110.x

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PRNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Creutzfeldt-Jakob disease risk and PRNP codon 129 polymorphism: necessity to revalue current data.PMID 16324095Read ↗

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PRNP variation in UK sporadic and variant Creutzfeldt Jakob disease highlights genetic risk factors and a novel non-synonymous polymorphism.Semantic proximity Read ↗

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