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Article

Genotyping of the prion protein gene at codon 129.

Acta neuropathologica - 1 Apr 1999

Zimmermann K, Turecek P L, Schwarz H P

Abstract excerpt

Sporadic, iatrogenic and new variant forms of Creutzfeldt-Jakob disease are associated with a predisposition for disease depending on a homozygosity at amino acid residue 129 of the prion protein gene (PRNP). A novel polymerase chain reaction/restriction digestion assay to screen for this polymorphism was developed and proved after comparison with a previously used method to be advantageous. Furthermore, for...

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Source

Identifiers

PMID: 10208274
DOI: 10.1007/s004010050998

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Genotyping of the prion protein gene at codon 129.PMID 10208274Read ↗

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Genetic risk factors associated with Creutzfeld-Jakob disease in Slovenians and a rapid typing for PRNP codon 129 single nucleotide polymorphism.Semantic proximity Read ↗

Codon 129 polymorphism of prion protein gene in sporadic Alzheimer's disease.Semantic proximity Read ↗

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