Article
Distribution of the M129V polymorphism of the prion protein gene in a Turkish population suggests a high risk for Creutzfeldt-Jakob disease.
European journal of human genetics : EJHG - 1 Dec 2001
Erginel-Unaltuna N, Peoc'h K, Komurcu E, Acuner T T, Issever H, Laplanche J L
Abstract excerpt
A polymorphism (M129V) at codon 129 of the prion protein gene (PRNP) results in either a methionine residue (Met) or a valine residue (Val) and is known to determine susceptibility for the development of sporadic or acquired Creutzfeldt-Jakob disease (CJD). The distributions of M129V genotypes and alleles in various general populations have been reported and there are clear differences between Western Europeans...
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