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Article

Polymorphic microsatellite sites in the PRNP region point to excess of homozygotes in Creutzfeldt-Jakob disease patients.

Gene - 1 Nov 2006

Geldermann Hermann, Bartenschlager Heinz, Preuss Siegfried, Melchinger-Wild Elke, Herzog Katja, Zerr Inga

Abstract excerpt

Polymorphic microsatellite sites within 148 kb of the human prion gene complex, including the genes PRNP, PRND and PRNT, were analysed together with the Codon129 variants regarding 50 CJD (Creutzfeldt-Jakob Disease) patients and 46 non-diseased control persons. Three of the sites (MM03, MM04, Codon129) differed significantly (P<0.05) for their allele frequencies between the two groups--the predominant allele...

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Source

Identifiers

PMID: 16889908
DOI: 10.1016/j.gene.2006.06.012

Genes

PRNP
PRND

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Polymorphic microsatellite sites in the PRNP region point to excess of homozygotes in Creutzfeldt-Jakob disease patients.PMID 16889908Read ↗

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