Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism of PRNP codons in the normal Icelandic population.

Acta neurologica Scandinavica - 1 Jun 2006

Georgsson G, Tryggvason T, Jonasdottir A D, Gudmundsson S, Thorgeirsdottir S

Abstract excerpt

OBJECTIVES: Polymorphisms in the prion protein gene in humans influence susceptibility to, and phenotype of, prion diseases. Methionine-methionine (MM) homozygosity at codon 129 is a risk factor for sporadic Creutzfeldt-Jakob disease (CJD). Polymorphism at codon 117 and changes in the octapeptide repeat region have been associated with genetic CJD. Knowledge of genetic background in normal populations may...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Distribution
Share to Amyloid
Share to Creutzfeldt-Jakob Syndrome

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Iceland

Share to Prion Proteins

Share to Prions

Share to Protein Precursors

Share to Sex Distribution

Source

Identifiers

PMID: 16674609
DOI: 10.1111/j.1600-0404.2006.00632.x

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism of PRNP codons in the normal Icelandic population.PMID 16674609Read ↗

Population distribution of the methionine allele at the PRNP codon 129 polymorphism in Europe and the Middle East.Semantic proximity Read ↗

The M129V polymorphism of codon 129 in the prion gene (PRNP) in the Danish population.Semantic proximity Read ↗

Analysis of PRNP gene codon 129 polymorphism in the Greek population.Semantic proximity Read ↗

PRNP variation in UK sporadic and variant Creutzfeldt Jakob disease highlights genetic risk factors and a novel non-synonymous polymorphism.Semantic proximity Read ↗

Polymorphisms of the prion protein gene in Italian patients with Creutzfeldt-Jakob disease.Semantic proximity Read ↗

Codon 129 polymorphism of the PRNP gene in normal Polish population and in Creutzfeldt-Jakob disease, and the search for new mutations in PRNP gene.Semantic proximity Read ↗

The influence of PRNP polymorphisms on human prion disease susceptibility: an update.Semantic proximity Read ↗

Creutzfeldt-Jakob disease risk and PRNP codon 129 polymorphism: necessity to revalue current data.Semantic proximity Read ↗

Polymorphisms of the prion protein gene (PRNP) in a Serbian population.Semantic proximity Read ↗

Genetic risk factors associated with Creutzfeld-Jakob disease in Slovenians and a rapid typing for PRNP codon 129 single nucleotide polymorphism.Semantic proximity Read ↗

Codon 129 polymorphism of prion protein gene in sporadic Alzheimer's disease.Semantic proximity Read ↗

The normal distribution of PRNP codon 129 polymorphism in the Moroccan population (Arabs and Casablanca residents).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.