Article
Sequence constancies and variations in genes encoding three new meningococcal vaccine candidate antigens.
Vaccine - 15 Mar 2006
Jacobsson Susanne, Thulin Sara, Mölling Paula, Unemo Magnus, Comanducci Maurizio, Rappuoli Rino, Olcén Per
Abstract excerpt
By the strategy "reverse vaccinology" a number of new antigens have been identified in Neisseria meningitidis, which are potential candidates for a highly needed broad-spectrum meningococcal vaccine. In the present study we examined the prevalence, sequence constancies and variations of the genes encoding three of these new antigens designated, genome-derived neisserial antigen (GNA) 1870, GNA1946 and GNA2132....
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