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Article

NadA, a novel vaccine candidate of Neisseria meningitidis.

The Journal of experimental medicine - 3 Jun 2002

Comanducci Maurizio, Bambini Stefania, Brunelli Brunella, Adu-Bobie Jeannette, Aricò Beatrice, Capecchi Barbara, Giuliani Marzia Monica, Masignani Vega, Santini Laura, Savino Silvana, Granoff Dan M, Caugant Dominique A, Pizza Mariagrazia, Rappuoli Rino, Mora Marirosa

Abstract excerpt

Neisseria meningitidis is a human pathogen, which, in spite of antibiotic therapy, is still a major cause of mortality due to sepsis and meningitis. Here we describe NadA, a novel surface antigen of N. meningitidis that is present in 52 out of 53 strains of hypervirulent lineages electrophoretic types (ET) ET37, ET5, and cluster A4. The gene is absent in the hypervirulent lineage III, in N. gonorrhoeae and in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12045242
DOI: 10.1084/jem.20020407
PMCID: PMC2193550

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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