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Telomerase RNA Accumulates in Cajal Bodies in Human Cancer Cells

7 Oct 2003

Abstract excerpt

Telomerase synthesizes telomeric DNA repeats at the ends of eukaryotic chromosomes. The RNA component of the enzyme (hTR) provides the template for telomere synthesis, which is catalyzed by telomerase reverse transcriptase (hTERT). Little is known regarding the subcellular localization of hTR and hTERT and the pathway by which telomerase is assembled. Here we report the first glimpse of the detailed subcellular...

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Share to Advanced biosensing and bioanalysis techniques
Share to RNA Interference and Gene Delivery
Share to Telomeres, Telomerase, and Senescence

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Identifiers

PMID: 14528011
DOI: 10.1091/mbc.e03-07-0525

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Telomerase RNA Accumulates in Cajal Bodies in Human Cancer CellsPMID 14528011Read ↗

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