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Article

Neurodegeneration: Impact of S-nitrosylated Parkin, DJ-1 and PINK1 on the pathogenesis of Parkinson's disease.

Archives of biochemistry and biophysics - 15 Jun 2021

Sircar Esha, Rai Sristi Raj, Wilson Mark A, Schlossmacher Michael G, Sengupta Rajib

Abstract excerpt

Parkinson's disease (PD) is one of the fastest-growing neurodegenerative disorders of increasing global prevalence. It represents the second most common movement disorder after tremor and the second most common neurodegenerative disorder after Alzheimer's disease. The incidence rate of idiopathic PD increases steadily with age, however, some variants of autosomal recessive inheritance are present with an early...

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PMID: 33819447
DOI: 10.1016/j.abb.2021.108869

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