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Article

Interactions between five candidate genes and antihypertensive drug therapy on blood pressure.

The pharmacogenomics journal - 1 Jan 2000

Schelleman H, Stricker B H Ch, Verschuren W M M, de Boer A, Kroon A A, de Leeuw P W, Kromhout D, Klungel O H

Abstract excerpt

Despite the availability of effective antihypertensive drugs, there is a large variation in response to these drugs. This study investigates whether polymorphisms in the angiotensin converting enzyme (I/D), angiotensinogen (M235T), alpha-adducin (G460W), angiotensin II type 1 receptor (1166A/C), or G protein beta(3)-subunit (825C/T) gene modify the mean difference in blood pressure levels among diuretics,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Calmodulin-Binding Proteins

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Share to Peptidyl-Dipeptidase A

Share to Receptor, Angiotensin, Type 1

Source

Identifiers

PMID: 16314886
DOI: 10.1038/sj.tpj.6500339

Genes

GNB3
ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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