Article
Gene-environment interactions of selected pharmacogenes in arterial hypertension.
Expert review of clinical pharmacology - 1 Nov 2012
Bochud Murielle, Guessous Idris
Abstract excerpt
Hypertension affects approximately 1 billion people worldwide. Owing to population aging, hypertension-related cardiovascular burden is expected to rise in the near future. In addition to genetic variants influencing the blood pressure response to antihypertensive drugs, several genes encoding for drug-metabolizing or -transporting enzymes have been associated with blood pressure and/or hypertension in humans...
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