Hoxd13 and Hoxa13 directly control the expression of the EphA7 Ephrin tyrosine kinase receptor in developing limbs.

doi:10.1074/jbc.M510900200

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Article

Hoxd13 and Hoxa13 directly control the expression of the EphA7 Ephrin tyrosine kinase receptor in developing limbs.

The Journal of biological chemistry - 27 Jan 2006

Salsi Valentina, Zappavigna Vincenzo

Abstract excerpt

Hoxa and Hoxd genes, related to the Drosophila Abd-B gene, display regionally restricted expression patterns and are necessary for the formation of the limb skeletal elements. Hox genes encode transcription factors, which are supposed to control the expression of a series of downstream target genes, whose nature has remained largely elusive. Several genes were identified that are differentially expressed in...

Topics

Amino Acid Sequence
Animals
Base Sequence
Binding Sites
Body Patterning
Chromatin Immunoprecipitation
Conserved Sequence
DNA
Ephrins
Escherichia coli
Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Extremities

Fibroblasts

Gene Expression Regulation, Developmental

Homeodomain Proteins

Luciferases

Mice

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 16314414
DOI: 10.1074/jbc.M510900200

Genes

HOXD13
HOXA13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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