Article
Candida albicans MTLalpha tup1Delta mutants can reversibly switch to mating-competent, filamentous growth forms.
Molecular microbiology - 1 Dec 2005
Park Yang-Nim, Morschhäuser Joachim
Abstract excerpt
Candida albicans strains that are homozygous at the mating type locus (MTLa or MTLalpha) can spontaneously switch from the normal round-to-oval yeast cell morphology to an elongated, so-called opaque cell form that can mate with opaque cells of the opposite mating type. In response to environmental signals, C. albicans also undergoes a transition from yeast to filamentous growth, which is negatively regulated by...
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