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Article

Control of filament formation in Candida albicans by the transcriptional repressor TUP1.

Science (New York, N.Y.) - 4 Jul 1997

Braun B R, Johnson A D

Abstract excerpt

The pathogenic yeast Candida albicans regulates its cellular morphology in response to environmental conditions. Ellipsoidal, single cells (blastospores) predominate in rich media, whereas filaments composed of elongated cells that are attached end-to-end form in response to starvation, serum, an...

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PMID: 9204892
DOI: 10.1126/science.277.5322.105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9204892-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Control of filament formation in Candida albicans by the transcriptional repressor TUP1.PMID 9204892Read ↗

Identification and characterization of TUP1-regulated genes in Candida albicans.Semantic proximity Read ↗

Induction of the<i>Candida albicans</i>Filamentous Growth Program by Relief of Transcriptional Repression: A Genome-wide AnalysisSemantic proximity Read ↗

HWP1 functions in the morphological development of Candida albicans downstream of EFG1, TUP1, and RBF1.Semantic proximity Read ↗

Candida albicans MTLalpha tup1Delta mutants can reversibly switch to mating-competent, filamentous growth forms.Semantic proximity Read ↗

A phenotypic profile of the Candida albicans regulatory network.Semantic proximity Read ↗

Ahr1 and Tup1 Contribute to the Transcriptional Control of Virulence-Associated Genes in Candida albicansSemantic proximity Read ↗

Finding a Missing Gene: EFG1 Regulates Morphogenesis in Candida tropicalis.Semantic proximity Read ↗

Wor1 establishes opaque cell fate through inhibition of the general co-repressor Tup1 in Candida albicans.Semantic proximity Read ↗

TupA, the Penicillium marneffei Tup1p homologue, represses both yeast and spore development.Semantic proximity Read ↗

Filamentation profile reveals several transcription regulators that contribute to differences between <i>Candida albicans</i> and <i>Candida dubliniensis</i>Semantic proximity Read ↗

Linkage of adhesion, filamentous growth, and virulence in Candida albicans to a single gene, INT1.Semantic proximity Read ↗

Candida albicans Ume6, a Filament-Specific Transcriptional Regulator, Directs Hyphal Growth via a Pathway Involving Hgc1 Cyclin-Related ProteinSemantic proximity Read ↗

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