Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Roles of TUP1 in switching, phase maintenance, and phase-specific gene expression in Candida albicans.

Eukaryotic cell - 1 Jun 2002

Zhao Rui, Lockhart Shawn R, Daniels Karla, Soll David R

Abstract excerpt

Candida albicans strain WO-1 switches spontaneously and reversibly between a "white" and "opaque" phenotype that affects colony morphology, cellular phenotype, and expression of a number of phase-specific genes and virulence traits. To assess the role of the transcription regulator Tup1p in this phenotypic transition, both TUP1 alleles were deleted in the mutant delta tup1. Delta tup1 formed "fuzzy large"...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Candida albicans
Share to DNA, Fungal
Share to Fungal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Gene Expression Regulation, Developmental

Share to Gene Expression Regulation, Fungal

Share to Genes, Fungal

Share to RNA, Fungal

Source

Open in PubMed Open full text

Identifiers

PMID: 12455984
DOI: 10.1128/EC.1.3.353-365.2002
PMCID: PMC118011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Roles of TUP1 in switching, phase maintenance, and phase-specific gene expression in Candida albicans.PMID 12455984Read ↗

Candida albicans MTLalpha tup1Delta mutants can reversibly switch to mating-competent, filamentous growth forms.Semantic proximity Read ↗

Wor1 establishes opaque cell fate through inhibition of the general co-repressor Tup1 in Candida albicans.Semantic proximity Read ↗

Analysis of phase-specific gene expression at the single-cell level in the white-opaque switching system of Candida albicans.Semantic proximity Read ↗

Developmental and molecular biology of switching in Candida albicans.Semantic proximity Read ↗

A white-specific gene in the white-opaque switching system of Candida albicans.Semantic proximity Read ↗

Role of the WOR1 Promoter of Candida albicans in Opaque Commitment.Semantic proximity Read ↗

Transcriptional control of C. albicans white-opaque switching and modulation by environmental cues and strain background.Semantic proximity Read ↗

Interlocking Transcriptional Feedback Loops Control White-Opaque Switching in Candida albicansSemantic proximity Read ↗

Bistable expression of WOR1, a master regulator of white-opaque switching in Candida albicans.Semantic proximity Read ↗

Temporal anatomy of an epigenetic switch in cell programming: the white‐opaque transition of C. albicansSemantic proximity Read ↗

White-opaque switching in Candida albicans: cell biology, regulation, and function.Semantic proximity Read ↗

Identification and Characterization of Wor4, a New Transcriptional Regulator of White-Opaque Switching.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.