Article
GABARAP is not essential for GABA receptor targeting to the synapse.
The European journal of neuroscience - 1 Nov 2005
O'Sullivan Gregory A, Kneussel Matthias, Elazar Zvulun, Betz Heinrich
Abstract excerpt
GABA(A) receptors (GABA(A)Rs) containing the gamma2 subunit are thought to require the interacting protein GABARAP (GABA(A)R associated protein) for trafficking to the neuronal plasma membrane. In order to assess whether GABARAP is required for GABA(A) receptor accumulation at synaptic sites, we analysed a GABARAP knockout mouse. GABARAP deficient mice are phenotypically normal and do not show up-regulation of...
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