Article
Dissociation of caspase-mediated events and programmed cell death induced via HLA-DR in follicular lymphoma.
Oncogene - 23 Mar 2006
Carmagnat M, Drénou B, Chahal H, Lord J M, Charron D, Estaquier J, Mooney N A
Abstract excerpt
Human leukocyte antigens (HLA) class II antigen-mediated apoptosis has been documented in antigen-presenting cells and B lymphoproliferations. Characteristics of the apoptosis include rapidity and selectivity for mature cells. Follicular lymphomas are particularly refractory to apoptosis. The B-cell lymphoma Ramos shares characteristics of this subgroup and is insensitive to apoptosis via simple HLA-DR...
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