Article
Transcriptional activity of Pax3 is co-activated by TAZ.
Biochemical and biophysical research communications - 13 Jan 2006
Murakami Masao, Tominaga Junji, Makita Ryosuke, Uchijima Yasunobu, Kurihara Yukiko, Nakagawa Osamu, Asano Tomoichiro, Kurihara Hiroki
Abstract excerpt
Pax3 is a transcription factor which functions in embryonic development and human diseases. In a yeast two-hybrid screen with full-length Pax3 as bait, we isolated a clone encoding transcriptional co-activator with PDZ-binding motif (TAZ) from an E10.5 mouse embryo cDNA library. Co-immunoprecipitation and nuclear co-localization of TAZ with Pax3 suggest that their association is functionally relevant. In situ...
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