Article
An interacting network of T-box genes directs gene expression and fate in the zebrafish mesoderm.
Proceedings of the National Academy of Sciences of the United States of America - 5 Aug 2003
Goering Lisa M, Hoshijima Kazuyuki, Hug Barbara, Bisgrove Brent, Kispert Andreas, Grunwald David Jonah
Abstract excerpt
T-box genes encode transcription factors that play critical roles in generating the vertebrate body plan. In many developmental fields, multiple T-box genes are expressed in overlapping domains, establishing broad regions in which different combinations of T-box genes are coexpressed. Here we demonstrate that three T-box genes expressed in the zebrafish mesoderm, no tail, spadetail, and tbx6, operate as a network...
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