Selection of minimum subsets of single nucleotide polymorphisms to capture haplotype block diversity.

doi:10.1142/9789812776303_0044

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Article

Selection of minimum subsets of single nucleotide polymorphisms to capture haplotype block diversity.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2003

Avi-Itzhak Hadar I, Su Xiaoping, De La Vega Francisco M

Abstract excerpt

We present a simple numerical algorithm to select the minimal subset of SNPs required to capture the diversity of haplotype blocks or other genetic loci. This algorithm can be used to quickly select the minimum SNP subset with no loss of haplotype information. In addition, the method can be used in a more aggressive mode to further reduce the original SNP set, with minimal loss of information. We demonstrate the...

Topics

Algorithms
Black People
Chromosomes, Human, Pair 21
Chromosomes, Human, Pair 22
Chromosomes, Human, Pair 6
Computational Biology
Databases, Genetic
Genetic Variation
Genome, Human
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Linkage Disequilibrium

Models, Genetic

Polymorphism, Single Nucleotide

White People

Black or African American

Source

Open in PubMed

Identifiers

PMID: 12603050
DOI: 10.1142/9789812776303_0044

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12603050-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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