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Article

Protective effect of the KCNMB1 E65K genetic polymorphism against diastolic hypertension in aging women and its relevance to cardiovascular risk.

Circulation research - 9 Dec 2005

Sentí Mariano, Fernández-Fernández José M, Tomás Marta, Vázquez Esther, Elosua Roberto, Marrugat Jaume, Valverde Miguel A

Abstract excerpt

The E65K polymorphism in the beta1-subunit of the large-conductance, Ca2+-dependent K+ (BK) channel, a key element in the control of arterial tone, has recently been associated with low prevalence of diastolic hypertension. We now report the modulatory effect of sex and age on the association of the E65K polymorphism with low prevalence of diastolic hypertension and the protective role of E65K polymorphism...

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Identifiers

PMID: 16293791
DOI: 10.1161/01.RES.0000196557.93717.95

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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