Article
Primary and immortalised human pancreatic islet endothelial cells: phenotypic and immunological characterisation.
Diabetologia - 1 Dec 2005
Favaro E, Bottelli A, Lozanoska-Ochser B, Ferioli E, Huang G C, Klein N, Chiaravalli A, Perin P Cavallo, Camussi G, Peakman M, Conaldi P G, Zanone M M
Abstract excerpt
AIMS/HYPOTHESIS: Studies on the biology of the microvascular endothelial cells (MECs) that surround and penetrate the pancreatic islets are hampered by difficulties in isolating and culturing large numbers of pure cells. We aimed to morphologically and functionally characterise primary MECs purified and cultured from human islets, and to establish a simian virus 40 (SV40)-immortalised cell line from these primary...
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