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Article

HMEC-1: establishment of an immortalized human microvascular endothelial cell line.

The Journal of investigative dermatology - 1 Dec 1992

Ades E W, Candal F J, Swerlick R A, George V G, Summers S, Bosse D C, Lawley T J

Abstract excerpt

The study of human microvascular endothelial cells has been limited, because these cells are difficult to isolate in pure culture, are fastidious in their in vitro growth requirements, and have a very limited lifespan. In order to overcome these difficulties, we have transfected human dermal microvascular endothelial cells (HMEC) with a PBR-322-based plasmid containing the coding region for the simian virus 40 A...

Topics

Antigens, Differentiation, Myelomonocytic
Antigens, Polyomavirus Transforming
Cell Adhesion
Cell Adhesion Molecules
Cell Line
Endothelium, Vascular
Humans
Intercellular Adhesion Molecule-1
Male
Microcirculation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Platelet Endothelial Cell Adhesion Molecule-1

T-Lymphocytes

Transfection

Source

Identifiers

PMID: 1361507
DOI: 10.1111/1523-1747.ep12613748

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1361507-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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