Article
Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo.
Blood - 1 Apr 2006
Sekyere Eric O, Dunn Louise L, Suryo Rahmanto Yohan, Richardson Des R
Abstract excerpt
Melanotransferrin (MTf) or tumor antigen p97 is a transferrin homolog that binds one iron (Fe) atom and has been suggested to play roles in a variety of processes, including Fe metabolism, eosinophil differentiation, and plasminogen activation. Considering the vital role of Fe in many metabolic pathways, such as DNA and heme synthesis, it is important to understand the function of MTf. To define this, a MTf...
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