Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo.

doi:10.1182/blood-2005-10-4174

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Article

Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo.

Blood - 1 Apr 2006

Sekyere Eric O, Dunn Louise L, Suryo Rahmanto Yohan, Richardson Des R

Abstract excerpt

Melanotransferrin (MTf) or tumor antigen p97 is a transferrin homolog that binds one iron (Fe) atom and has been suggested to play roles in a variety of processes, including Fe metabolism, eosinophil differentiation, and plasminogen activation. Considering the vital role of Fe in many metabolic pathways, such as DNA and heme synthesis, it is important to understand the function of MTf. To define this, a MTf...

Topics

Animals
Antigens, Neoplasm
DNA
Genotype
Heme
Iron
Kidney
Liver
Melanoma-Specific Antigens
Mice
Mice, Knockout
Myocardium
Neoplasm Proteins
Reverse Transcriptase Polymerase Chain Reaction
Spleen

Source

Open in PubMed

Identifiers

PMID: 16291590
DOI: 10.1182/blood-2005-10-4174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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