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Article

Heme oxygenase 1 is required for mammalian iron reutilization.

Proceedings of the National Academy of Sciences of the United States of America - 30 Sept 1997

Poss K D, Tonegawa S

Abstract excerpt

The majority of iron for essential mammalian biological activities such as erythropoiesis is thought to be reutilized from cellular hemoproteins. Here, we generated mice lacking functional heme oxygenase 1 (Hmox1; EC 1.14.99.3), which catabolizes heme to biliverdin, carbon monoxide, and free iron...

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Identifiers

PMID: 9380735
DOI: 10.1073/pnas.94.20.10919
PMCID: PMC23531

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9380735-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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