Article
Toenail iron, genetic determinants of iron status, and the risk of glioma.
Cancer causes & control : CCC - 1 Dec 2013
Anic Gabriella M, Madden Melissa H, Thompson Reid C, Nabors L Burton, Olson Jeffrey J, Larocca Renato V, Browning James E, Brockman John D, Forsyth Peter A, Egan Kathleen M
Abstract excerpt
PURPOSE: Iron is essential for oxygen transport and oxidative metabolism; however, elevated iron stores can trigger overproduction of reactive oxygen species and induce DNA damage. Little is known about the association between body iron stores and glioma risk. This study examined the associations of iron levels measured in toenails and genetic variants linked to body iron stores with risk of glioma in a...
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