Article
Inhibition of drug-resistant HIV-1 by RNA interference.
Antiviral research - 1 Jan 2006
Huelsmann Peter M, Rauch Pia, Allers Kristina, John Matthias J, Metzner Karin J
Abstract excerpt
RNA interference is a powerful tool used to inhibit human immunodeficiency virus type 1 (HIV-1) replication in vitro. Almost all HIV-1 genes have been targets for small interfering RNA (siRNA) molecules, and HIV-1 replication can be specifically and successfully inhibited by this technique. RNA interference has been proposed as an alternative strategy to inhibit replication of drug-resistant viruses that emerge...
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