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Article

Clonal analysis of HIV-1 variants in proviral DNA during treatment interruption in patients with multiple therapy failures.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Dec 2005

Boucher Sébastien, Recordon-Pinson Patricia, Neau Didier, Ragnaud Jean-Marie, Titier Karine, Faure Muriel, Fleury Hervé, Masquelier Bernard

Abstract excerpt

BACKGROUND: Treatment interruption (TI) in antiretroviral-treated patients on virological failure (VF) often results in a shift from resistant to wild-type HIV-1 in plasma. A clonal analysis was set out to determine the importance of archiving of resistant HIV-1 variants during TI and its relationship with the occurrence of a VF after treatment resumption. METHODS: A fragment of the pol gene was cloned and...

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Share to Anti-HIV Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16286052
DOI: 10.1016/j.jcv.2005.01.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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