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Characterization of Adeno-Associated Virus Genomes Isolated from Human Tissues

10 Nov 2005

Abstract excerpt

Infection with wild-type adeno-associated virus (AAV) is common in humans, but very little is known about the in vivo biology of AAV. On a molecular level, it has been shown in cultured cells that AAV integrates in a site-specific manner on human chromosome 19, but this has never been demonstrated directly in infected human tissues. To that end, we tested 175 tissue samples for the presence of AAV DNA, and when...

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Identifiers

PMID: 16282479
DOI: 10.1128/jvi.79.23.14793-14803.2005

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