Article

Site-specific integration by adeno-associated virus.

1996-10-15

Abstract excerpt

Adeno-associated virus (AAV) has attracted considerable interest as a potential vector for gene delivery. Wild-type virus is notable for the lack of association with any human disease and the ability to stably integrate its genome in a site-specific manner in a locus on human chromosome 19 (AAVS1). Use of a functional model system for AAV DNA integration into AAVS1 has allowed us to conclude that the recombination...

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Literature Corpus work: eaf0e6bd-c723-55cf-892d-65eca54721bc
DOI: 10.1073/pnas.93.21.11288

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