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Molecular Characterization of Adeno-Associated Viruses Infecting Children

10 Nov 2005

Abstract excerpt

Although adeno-associated virus (AAV) infection is common in humans, the biology of natural infection is poorly understood. Since it is likely that many primary AAV infections occur during childhood, we set out to characterize the frequency and complexity of circulating AAV isolates in fresh and archived frozen human pediatric tissues. Total cellular DNA was isolated from 175 tissue samples including freshly...

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PMID: 16282478
DOI: 10.1128/jvi.79.23.14781-14792.2005

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