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Adeno-associated virus infection and its impact in human health: an overview

31 Oct 2022

Abstract excerpt

Discovered as a contaminant of adenovirus stocks in the 1960s, adeno-associated virus (AAV) is a mono-stranded DNA virus that depends on helper factors to replicate. Even though AAV is endemic in the human population (35-80%), it is remarkable that many issues concerning the natural infection by this virus remain unanswered. In this study, we reflect on the main basic aspects of AAV biology and provide an...

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PMID: 36316711
DOI: 10.1186/s12985-022-01900-4

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