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Article

XRCC1 polymorphism and lung cancer risk in relation to tobacco smoking.

International journal of molecular medicine - 1 Oct 2005

Schneider Joachim, Classen Vera, Bernges Ulrike, Philipp Monika

Abstract excerpt

DNA repair plays a critical role in protecting the genome of the cell from carcinogens or ionising radiation. Reduced DNA-repair capacity can increase susceptibility to occupational-induced cancer. Three coding polymorphisms at codons 194, 280, and 399 in X-ray cross complementing group 1 (XRCC1) DNA-repair gene have been identified, and it is possible that these polymorphisms may affect DNA- repair capacity and...

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Source

Identifiers

PMID: 16142409

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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