Article
Human sinonasal epithelial cells direct dendritic function and T-cell T helper 1/T helper 2 skewing following Aspergillus exposure.
International forum of allergy & rhinology - 1 Jan 2000
Mulligan Jennifer K, Mulligan Ryan M, Atkinson Carl, Schlosser Rodney J
Abstract excerpt
BACKGROUND: In lower airway disease such as asthma, epithelial cells have been shown to be potent regulators of dendritic cell (DC) functions. However, it is unclear how human sinonasal epithelial cells (HSNECs) from patients with sinusitis regulate DC functions. Therefore, in these studies we investigated the ability of Aspergillus fumigatus exposed HSNECs to regulate DC antigen uptake, maturation, and direction...
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