Article
Detection of circulating tumor cells in colorectal cancer by immunobead-PCR is a sensitive prognostic marker for relapse of disease.
Molecular medicine (Cambridge, Mass.) - 1 Nov 1995
Hardingham J E, Kotasek D, Sage R E, Eaton M C, Pascoe V H, Dobrovic A
Abstract excerpt
BACKGROUND: Recurrent and metastatic carcinoma of the colorectum remains a major problem, with survival at 5 years post curative resection still only about 50%. Moreover, up to 30% of patients who present with early stage disease also relapse and die within 5 years, suggesting the presence of micrometastatic disease at diagnosis. One route of metastatic spread is via the blood stream, hence the detection of tumor...
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