Article
Detection of circulating tumor cells in colorectal cancer by immunobead-PCR is a sensitive prognostic marker for relapse of disease.
Molecular medicine (Cambridge, Mass.) - 1 Nov 1995
Hardingham J E, Kotasek D, Sage R E, Eaton M C, Pascoe V H, Dobrovic A
Abstract excerpt
BACKGROUND: Recurrent and metastatic carcinoma of the colorectum remains a major problem, with survival at 5 years post curative resection still only about 50%. Moreover, up to 30% of patients who present with early stage disease also relapse and die within 5 years, suggesting the presence of mic...
Topics
- Aged
- Aged, 80 and over
- Carcinoma
- Colorectal Neoplasms
- Disease-Free Survival
- Female
- Genes, ras
- Humans
- Male
- Middle Aged
- Mutation
- Neoplasm Metastasis
- Neoplastic Cells, Circulating
- Polymerase Chain Reaction
- Recurrence