Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Admixture-matched case-control study: a practical approach for genetic association studies in admixed populations.

Human genetics - 1 Jan 2006

Tsai Hui-Ju, Kho Jennifer Y, Shaikh Nishat, Choudhry Shweta, Naqvi Mariam, Navarro Daniel, Matallana Henry, Castro Richard, Lilly Craig M, Watson H George, Meade Kelley, Lenoir Michael, Thyne Shannon, Ziv Elad, Burchard Esteban González

Abstract excerpt

Case-control genetic association studies in admixed populations are known to be susceptible to genetic confounding due to population stratification. The transmission/disequilibrium test (TDT) approach can avoid this problem. However, the TDT is expensive and impractical for late-onset diseases. Case-control study designs, in which, cases and controls are matched by admixture, can be an appealing and a suitable...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma
Share to Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Black People

Share to Case-Control Studies

Share to Confounding Factors, Epidemiologic

Share to Demography

Share to Receptors, Adrenergic, beta-2

Source

Open in PubMed Open full text

Identifiers

PMID: 16273390
DOI: 10.1007/s00439-005-0080-2
PMCID: PMC3478103

Genes

FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Admixture-matched case-control study: a practical approach for genetic association studies in admixed populations.PMID 16273390Read ↗

Mapping asthma-associated variants in admixed populationsSemantic proximity Read ↗

Admixture mapping identifies a quantitative trait locus associated with FEV1/FVC in the COPDGene Study.Semantic proximity Read ↗

Gene Mapping in Admixed Families: A Cautionary Note on the Interpretation of the Transmission Disequilibrium Test and a Possible Solution.Semantic proximity Read ↗

Admixture mapping and the role of population structure for localizing disease genes.Semantic proximity Read ↗

Mapping of disease-associated variants in admixed populations.Semantic proximity Read ↗

Mixed-model admixture mapping identifies smoking-dependent loci of lung function in African AmericansSemantic proximity Read ↗

Case-control admixture mapping in Latino populations enriches for known asthma-associated genes.Semantic proximity Read ↗

Statistical tests for admixture mapping with case-control and cases-only data.Semantic proximity Read ↗

Genomic Regions 10q22.2, 17q21.31, and 2p23.1 Can Contribute to a Lower Lung Function in African Descent Populations.Semantic proximity Read ↗

Confounding and heterogeneity in genetic association studies with admixed populations.Semantic proximity Read ↗

Implications of population structure and ancestry on asthma genetic studies.Semantic proximity Read ↗

African Americans with asthma: genetic insights.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.