Article
Increased susceptibility to apoptosis of CD56dimCD16+ NK cells induces the enrichment of IFN-gamma-producing CD56bright cells in tuberculous pleurisy.
Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2005
Schierloh Pablo, Yokobori Noemí, Alemán Mercedes, Musella Rosa M, Beigier-Bompadre Macarena, Saab María A, Alves Leandro, Abbate Eduardo, de la Barrera Silvia S, Sasiain María C
Abstract excerpt
Tuberculous pleuritis is a good model for the study of specific cells at the site of active Mycobacterium tuberculosis (Mtb) infection. We investigated the frequency and phenotype of NK cells in paired samples of peripheral blood and pleural fluid (PF) from patients with tuberculosis (TB) or parapneumonic infection. We demonstrated for the first time a reduction of NK cells in PF from TB with an enrichment in the...
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