Article
Associations of uric acid with polymorphisms in the delta-aminolevulinic acid dehydratase, vitamin D receptor, and nitric oxide synthase genes in Korean lead workers.
Environmental health perspectives - 1 Nov 2005
Weaver Virginia M, Schwartz Brian S, Jaar Bernard G, Ahn Kyu-Dong, Todd Andrew C, Lee Sung-Soo, Kelsey Karl T, Silbergeld Ellen K, Lustberg Mark E, Parsons Patrick J, Wen Jiayu, Lee Byung-Kook
Abstract excerpt
Recent research suggests that uric acid may be nephrotoxic at lower levels than previously recognized and that it may be one mechanism for lead-related nephrotoxicity. Therefore, in understanding mechanisms for lead-related nephrotoxicity, it would be of value to determine whether genetic polymorphisms that are associated with renal outcomes in lead workers and/or modify associations between lead dose and renal...
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